Main line
The crossword clue "Main line" is answered by AORTA, a 5-letter entry. Used 42 times across 24 distinct years; most recently in 2026; first recorded in 1993. It appears in 9 publications in the xd corpus. Every figure on this page comes from the collection data itself.
The answer
AORTA
5 letters. See every clue for this answer on the AORTA answer page.
Used 42 times across 24 distinct years; most recently in 2026; first recorded in 1993. It appears in 9 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.
Other answers for this clue
The same clue has also been answered these ways in the xd corpus. Answers inside this collection link to their own answer page.
- ARTERY (5 uses in xd)
- GASPIPE (1 uses in xd)
Other clues for AORTA
Every other clue in this collection answered by AORTA, most used first.
- Main artery - used 220 times, most recently in 2026
- Major artery - used 132 times, most recently in 2026
- It comes from the heart - used 108 times, most recently in 2026
- Blood line - used 92 times, most recently in 2026
- Major blood vessel - used 92 times, most recently in 2026
- Heart line - used 72 times, most recently in 2026
- Vital artery - used 48 times, most recently in 2026
- Vital vessel - used 42 times, most recently in 2025
- Largest artery - used 40 times, most recently in 2026
Related clues
Clues in this collection of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.
- Line dance - CONGA, used 59 times
- Main impact - BRUNT, used 42 times
- Main points - GISTS, used 38 times
- Line of cliffs - SCARP, used 36 times
- Toes the line - OBEYS, used 36 times
- "___ Line Is It Anyway?" - WHOSE, used 29 times
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