Largest artery
The crossword clue "Largest artery" is answered by AORTA, a 5-letter entry. Used 40 times across 17 distinct years; most recently in 2026; first recorded in 1945. It appears in 12 publications in the xd corpus. Every figure on this page comes from the collection data itself.
The answer
AORTA
5 letters. See every clue for this answer on the AORTA answer page.
Used 40 times across 17 distinct years; most recently in 2026; first recorded in 1945. It appears in 12 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.
Other clues for AORTA
Every other clue in this collection answered by AORTA, most used first.
- Main artery - used 220 times, most recently in 2026
- Major artery - used 132 times, most recently in 2026
- It comes from the heart - used 108 times, most recently in 2026
- Blood line - used 92 times, most recently in 2026
- Major blood vessel - used 92 times, most recently in 2026
- Heart line - used 72 times, most recently in 2026
- Vital artery - used 48 times, most recently in 2026
- Main line - used 42 times, most recently in 2026
- Vital vessel - used 42 times, most recently in 2025
Related clues
Clues in this collection of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.
- Nebraska's largest city - OMAHA, used 104 times
- Largest Greek island - CRETE, used 62 times
- Saturn's largest moon - TITAN, used 48 times
- Artery opener - STENT, used 30 times
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