Major artery
The crossword clue "Major artery" is answered by AORTA, a 5-letter entry. Used 132 times across 35 distinct years; most recently in 2026. It appears in 31 publications in the xd corpus. Every figure on this page comes from the pilot data itself.
The answer
AORTA
5 letters. See every clue for this answer on the AORTA answer page.
Used 132 times across 35 distinct years; most recently in 2026. It appears in 31 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.
Other answers for this clue
The same clue has also been answered these ways in the xd corpus. Answers inside this pilot link to their own answer page.
- CAROTID (7 uses in xd)
- FREEWAY (2 uses in xd)
- TURNPIKE (2 uses in xd)
- MAINROAD (1 uses in xd)
Other clues for AORTA
Every other clue in this pilot answered by AORTA, most used first.
- Main artery - used 220 times, most recently in 2026
- It comes from the heart - used 108 times, most recently in 2026
- Blood line - used 92 times, most recently in 2026
- Major blood vessel - used 92 times, most recently in 2026
Related clues
Pilot clues of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.
- Make amends - ATONE, used 664 times
- In the know - AWARE, used 356 times
- Battery terminal - ANODE, used 319 times
- Book of maps - ATLAS, used 317 times
- Buenos ___ - AIRES, used 315 times
- Accumulate - AMASS, used 311 times
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