Toxic substance
The crossword clue "Toxic substance" is answered by POISON, a 6-letter entry. Used 10 times across 7 distinct years; most recently in 2025; first recorded in 2012. It appears in 5 publications in the xd corpus. Every figure on this page comes from the collection data itself, never from a guess.
The answer
POISON
6 letters. See every clue for this answer on the POISON answer page.
Used 10 times across 7 distinct years; most recently in 2025; first recorded in 2012. It appears in 5 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.
Other answers for this clue
The same clue has also been answered these ways in the xd corpus. Answers inside this collection link to their own answer page.
- VENIN (1 uses in xd)
Other clues for POISON
Every other clue in this collection answered by POISON, most used first.
- Skull-and-crossbones stuff - used 6 times, most recently in 2014
Related clues
Clues in this collection of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.
- High-pH substance - ALKALI, used 10 times
- Dissolved substance - SOLUTE, used 9 times
- Sand substance - SILICA, used 7 times
- Substance - MATTER, used 6 times
- Substance used to curdle milk - RENNET, used 6 times
- Tooth substance - DENTIN, used 6 times
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