Most significant
The crossword clue "Most significant" is answered by MAIN, a 4-letter entry. Used 7 times across 6 distinct years; most recently in 2025; first recorded in 2012. It appears in 1 publications in the xd corpus. Every figure on this page comes from the collection data itself, never from a guess.
The answer
MAIN
4 letters. See every clue for this answer on the MAIN answer page.
Used 7 times across 6 distinct years; most recently in 2025; first recorded in 2012. It appears in 1 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.
Other clues for MAIN
Every other clue in this collection answered by MAIN, most used first.
- Primary - used 148 times, most recently in 2026
- Principal - used 64 times, most recently in 2026
- Common street name - used 55 times, most recently in 2026
- Chief - used 49 times, most recently in 2026
- Most important - used 35 times, most recently in 2026
- Water carrier - used 24 times, most recently in 2026
- Popular street name - used 18 times, most recently in 2015
- Central - used 13 times, most recently in 2026
- Water pipe - used 12 times, most recently in 2025
- Conduit - used 11 times, most recently in 1996
- Cardinal - used 10 times, most recently in 2011
- Water conduit - used 10 times, most recently in 2026
- Big water pipe - used 9 times, most recently in 2026
- Key - used 8 times, most recently in 2024
- Foremost - used 7 times, most recently in 2025
- Kind of a drag? - used 7 times, most recently in 2026
- Major water pipe - used 7 times, most recently in 2026
- Predominant - used 6 times, most recently in 2025
Related clues
Clues in this collection of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.
- Most populous continent - ASIA, used 61 times
- Where most people live - ASIA, used 45 times
- Significant periods - ERAS, used 40 times
- Most populous Hawaiian island - OAHU, used 32 times
- Significant times - ERAS, used 31 times
- Significant stretches - ERAS, used 25 times
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