Inflammation suffix

The answer

ITIS

4 letters. See every clue for this answer on the ITIS answer page.

Used 20 times across 16 distinct years; most recently in 2022; first recorded in 1951. It appears in 8 publications in the xd corpus. Frequency and last-seen figures come from the xd crossword corpus only.

Other clues for ITIS

Every other clue in this collection answered by ITIS, most used first.

• "How sweet ___!" - used 140 times, most recently in 2026
• Medical suffix - used 44 times, most recently in 2026
• "Really?" - used 29 times, most recently in 2026
• "Indeed" - used 23 times, most recently in 2026
• "You know how ___" - used 17 times, most recently in 2025
• Tell it like ___ - used 15 times, most recently in 2025
• "___ later than you think." - used 13 times, most recently in 1968
• Reply to "That so?" - used 13 times, most recently in 2026
• "No kidding?" - used 12 times, most recently in 2026
• Gleason's "How sweet ___!" - used 11 times, most recently in 2011
• "Correct" - used 10 times, most recently in 2026
• "___ to laugh": Pinero - used 9 times, most recently in 1991
• "How sweet ___!": Gleason - used 8 times, most recently in 2003
• Suffix with "senior" - used 8 times, most recently in 2024
• Suffix with sinus - used 8 times, most recently in 2024
• "That's just the way ___" - used 8 times, most recently in 2024
• "___ an ancient Mariner . . . " - used 7 times, most recently in 1993
• End of an illness? - used 7 times, most recently in 2018
• Reply to "That a fact?" - used 7 times, most recently in 2021
• Suffix for "senior" - used 7 times, most recently in 2025
• Terse confirmation - used 7 times, most recently in 2026
• "That's the way __" - used 6 times, most recently in 2016
• Tonsil attachment? - used 6 times, most recently in 2016
• Words before and after "what" - used 6 times, most recently in 2025

Related clues

Clues in this collection of the same answer length that share a word with this clue, or match its answer pattern when no word is shared. Most used first.

• Diminutive suffix - ETTE, used 278 times
• Feminine suffix - ETTE, used 128 times
• Noun suffix. - ENCE, used 83 times
• Suffix for kitchen - ETTE, used 78 times
• Feminine suffix - ENNE, used 77 times
• Slangy suffix - EROO, used 76 times

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